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LITERATURE REVIEW: CANDIDA GLABRATA

Introduction: Candida Glabrata, species of the Candida group, called non-albicans, is responsible for several infections that are difficult to treat. It is opportunistic and targets immunocompromised individuals. The diagnosis is made through the analysis of vaginal discharge, followed by a treatment that guarantees the improvement of symptoms. Goals: This review aims to expose conclusions about the pathogen Candida Glabrata and elucidate the management of cases. Methods: This is an integrative literature review. It included selected research between 1991 and 2020, a total of 17 studies. Inclusion and exclusion criteria were selected and the search was carried out through databases of renowned platforms. Results: The various types of Candida are commensal beings and are part of the vaginal microbiota, however, when there is an imbalance in immunity, they proliferate, causing symptoms. Glabrata became known for its aggressiveness and resistance to treatment with Fluconazole. Its diagnosis is made through clinical examination and laboratory tests of vaginal discharge that confirm the type of Candida that the individual has, helping in the correct treatment.Conclusion: Candida Glabrata is still a diagnostic hypothesis not explored by health professionals, due to the lack of information on the subject. It is considered a saprophyte of the vagina and presents a clinical picture when there is an immunological imbalance in the patient. Furthermore, it is resistant to treatment with Fluconazole and responds well to the use of Flucytosine. It is necessary to demystify the subject so that patients receive adequate care.

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LITERATURE REVIEW: CANDIDA GLABRATA

  • DOI: 10.22533/at.ed.1593102307029

  • Palavras-chave: Candida Glabrata; Vulvovaginal Candidiasis; Vaginitis; Health; Women's Health.

  • Keywords: Candida Glabrata; Vulvovaginal Candidiasis; Vaginitis; Health; Women's Health.

  • Abstract:

    Introduction: Candida Glabrata, species of the Candida group, called non-albicans, is responsible for several infections that are difficult to treat. It is opportunistic and targets immunocompromised individuals. The diagnosis is made through the analysis of vaginal discharge, followed by a treatment that guarantees the improvement of symptoms. Goals: This review aims to expose conclusions about the pathogen Candida Glabrata and elucidate the management of cases. Methods: This is an integrative literature review. It included selected research between 1991 and 2020, a total of 17 studies. Inclusion and exclusion criteria were selected and the search was carried out through databases of renowned platforms. Results: The various types of Candida are commensal beings and are part of the vaginal microbiota, however, when there is an imbalance in immunity, they proliferate, causing symptoms. Glabrata became known for its aggressiveness and resistance to treatment with Fluconazole. Its diagnosis is made through clinical examination and laboratory tests of vaginal discharge that confirm the type of Candida that the individual has, helping in the correct treatment.Conclusion: Candida Glabrata is still a diagnostic hypothesis not explored by health professionals, due to the lack of information on the subject. It is considered a saprophyte of the vagina and presents a clinical picture when there is an immunological imbalance in the patient. Furthermore, it is resistant to treatment with Fluconazole and responds well to the use of Flucytosine. It is necessary to demystify the subject so that patients receive adequate care.

  • Cricia Daniely Ferreira
  • Ana Laura Martins Fragoso Maia
  • Donizete dos Reis Andrade Júnior
  • Giovanna Cristina Marques Andrade
  • Jéssica Karolline Vieira Sandoville
  • Lara Laís da Silva Santos
  • Letícia Faria Araújo
  • Marcella de Castro Rodrigues
  • Mariana Fernandes Santos
  • Mariana Pereira Morais Oliveira
  • Rafaela Pereira Nascimento
  • Sara Bastos Santos
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