PREPARATION OF PARAFFIN MICROSPHERES BY SUSPENSION USING PVP AS A STABILIZING AGENT
The present work aimed at the production of paraffin microspheres, which have the function of acting as a porogenic agent in the manufacture of porous scaffolds. The experimental tests were carried out in suspended systems. Subsequently, the influence of 3 process factors was evaluated using experimental planning techniques: A) Concentration of sodium sulfate as coagulant (3 and 9 g/L), B) Concentration of poly(vinyl pyrrolidone) (PVP) as stabilizer (4 and 12g/L) and C) Agitation (500 and 600 rpm).
The best results obtained for the diameter of the paraffin particles were from 750 to 550 m, for the 3 dependent variables d 10 , d 32 and d 43 , obtained with agitation from 580 to 640 rpm (levels 0.9 to 1.2). Since to obtain particles with smaller diameters, the increase in the concentration of PVP is important together with the increase in agitation.
PREPARATION OF PARAFFIN MICROSPHERES BY SUSPENSION USING PVP AS A STABILIZING AGENT
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DOI: 10.22533/at.ed.3173122324041
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Palavras-chave: microspheres, paraffin, PVP, suspension
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Keywords: microspheres, paraffin, PVP, suspension
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Abstract:
The present work aimed at the production of paraffin microspheres, which have the function of acting as a porogenic agent in the manufacture of porous scaffolds. The experimental tests were carried out in suspended systems. Subsequently, the influence of 3 process factors was evaluated using experimental planning techniques: A) Concentration of sodium sulfate as coagulant (3 and 9 g/L), B) Concentration of poly(vinyl pyrrolidone) (PVP) as stabilizer (4 and 12g/L) and C) Agitation (500 and 600 rpm).
The best results obtained for the diameter of the paraffin particles were from 750 to 550 m, for the 3 dependent variables d 10 , d 32 and d 43 , obtained with agitation from 580 to 640 rpm (levels 0.9 to 1.2). Since to obtain particles with smaller diameters, the increase in the concentration of PVP is important together with the increase in agitation.
- GERSON AVELINO FERNANDES
- Karine Lopes Resende
- Toni Jefferson Lopes
