PEDIATRIC NECROTIZING PNEUMONIA PEDIATRIC NECROTIZING PNEUMONIA
Objective: To analyze the factors associated with Pediatric Necrotizing Pneumonia, addressing diagnostic strategies, treatment options and the main clinical outcomes observed. Methodology: A literature review using the PubMed - MEDLINE electronic database. The search terms included "pediatrics", "necrotizing pneumonia" and their combinations. After screening, 15 articles were included in the analysis. Results: The main factors influencing the diagnosis of NPP include the overlap of symptoms between etiologic agents, making it challenging to differentiate between Mycoplasma pneumoniae and other causes. Methods such as lung ultrasound and radiomics applied to tomography are promising for early identification. Inflammatory biomarkers, such as MLR, PLR, neutrophilia and elevated D-dimer, help with risk stratification and predicting severity. Prolonged antibiotic therapy remains the mainstay of therapy, but the need for invasive interventions, such as pleural drainage and surgery, is controversial and depends on severity. Prognosis is associated with speed of diagnosis, response to treatment, age and comorbidities. Pneumococcal vaccination has reduced hospitalizations, but the persistence of resistant serotypes requires continuous epidemiological monitoring. Final considerations : PNP requires an individualized approach and agile diagnosis to reduce complications and optimize outcomes. Future studies should focus on identifying biomarkers, optimizing therapy and standardizing protocols to improve management.
PEDIATRIC NECROTIZING PNEUMONIA PEDIATRIC NECROTIZING PNEUMONIA
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DOI: https://doi.org/10.22533/at.ed.15951625240313
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Palavras-chave: Pediatric Necrotizing Pneumonia; Mycoplasma pneumoniae; Diagnosis; Treatment.
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Keywords: Pediatric Necrotizing Pneumonia; Mycoplasma pneumoniae; Diagnosis; Treatment.
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Abstract:
Objective: To analyze the factors associated with Pediatric Necrotizing Pneumonia, addressing diagnostic strategies, treatment options and the main clinical outcomes observed. Methodology: A literature review using the PubMed - MEDLINE electronic database. The search terms included "pediatrics", "necrotizing pneumonia" and their combinations. After screening, 15 articles were included in the analysis. Results: The main factors influencing the diagnosis of NPP include the overlap of symptoms between etiologic agents, making it challenging to differentiate between Mycoplasma pneumoniae and other causes. Methods such as lung ultrasound and radiomics applied to tomography are promising for early identification. Inflammatory biomarkers, such as MLR, PLR, neutrophilia and elevated D-dimer, help with risk stratification and predicting severity. Prolonged antibiotic therapy remains the mainstay of therapy, but the need for invasive interventions, such as pleural drainage and surgery, is controversial and depends on severity. Prognosis is associated with speed of diagnosis, response to treatment, age and comorbidities. Pneumococcal vaccination has reduced hospitalizations, but the persistence of resistant serotypes requires continuous epidemiological monitoring. Final considerations : PNP requires an individualized approach and agile diagnosis to reduce complications and optimize outcomes. Future studies should focus on identifying biomarkers, optimizing therapy and standardizing protocols to improve management.
- Thaís Araújo dos Santos
- Mariana Fonseca Melo
- Rianny Faria de Freitas
- Ana Julia Machado
- Mariana Khatarinne de Menezes Pereira
- Brunna Bchara Giroldo
- Maria Luiza Miranda Sanches
- Jéssica Hipólito Castilhas
- Larissa Alves Dutra Morato
- Maria Luíza Borba de M Silva
- Isabella Mourad Zenardi
- Mariana Luísa da Silva Azevedo