PERSPECTIVES OF UTERUS TRANSPLANTATION IN THE TREATMENT OF INFERTILITY: A LITERATURE REVIEW

• DOI: 10.22533/at.ed.1592802209121

• Palavras-chave: Uterus; Transplant; Surgery.

• Keywords: Uterus; Transplant; Surgery.

• Abstract:

  Absolute uterine factor infertility (AUFI) may have uterine transplantation (UT) as a therapeutic approach. The practical application faces challenges associated with the complexity of the procedure, ethical concepts and anatomical difficulties. Objective: To discuss the effectiveness and challenges of UT as a safe surgical treatment for uterine infertility in women of childbearing age. Methodology: Bibliographic review carried out based on searches in the PubMed and SciELO databases, of which 12 studies were considered to compose the collection after applying inclusion and exclusion criteria. Review: The choice of a living or deceased donor must undergo a thorough screening in terms of anamnesis, laboratory and anatomy. Postoperative complications, psychological factors and complications related to fetal development may occur. Regarding the success of the procedure, it was observed that UT from living donors obtained better results than those from deceased donors and most complications are due to vascular causes. Final Considerations: UT is an innovative therapeutic option, however, it is still considered an experimental procedure with positive results for future research.