Mucous membrane pemphigoid with oral mucosa manifestations: case report

• DOI: https://doi.org/10.22533/at.ed.1594912414106

• Palavras-chave: Autoimmune diseases. Oral health. Laser. Pathology.

• Keywords: Autoimmune diseases. Oral health. Laser. Pathology.

• Abstract:

  Mucous membrane pemphigoid represents a group of chronic mucocutaneous bullous diseases of autoimmune origin, in which tissue-bound autoantibodies cause the destruction of basement membrane components. Oral lesions are usually the first to be observed, but other sites may be involved, such as the conjunctival, nasal, esophageal, laryngeal and vaginal mucous membranes, as well as the skin. The clinical characteristic of the lesions are blisters or vesicles, which later rupture leaving an area of superficial ulceration. In general, this clinical manifestation is seen diffusely in the mouth, but may be limited to a specific site, the gums being the most frequent. Gingival involvement forms a clinical pattern called desquamative gingivitis, which can also be seen in other immune-mediated conditions such as erosive lichen planus and pemphigus vulgaris. It is therefore of the utmost importance for dentists to know the main oral manifestations of autoimmune diseases, as well as the various etiologies that desquamative gingivitis can present. The aim of this study is to report two clinical cases of mucous membrane pemphigoid, with oral and gingival manifestations, in order to help dentists diagnose and treat this pathology.