Ocular and Nasal Involvement in Sjögren's Syndrome: A Cross-Specialty Literature Review

• DOI: https://doi.org/10.22533/at.ed.15948424160910

• Palavras-chave: Síndrome de Sjögren; Envolvimento Ocular; Sintomas Nasais; Revisão Interdisciplinar; Doença Autoimune.

• Keywords: Sjögren's Syndrome; Ocular Involvement; Nasal Symptoms; Cross-Specialty Review; Autoimmune Disease.

• Abstract: Abstract Objectives: This literature review aims to synthesize information from various specialties to enhance the understanding and management of ocular and nasal symptoms in Sjögren's Syndrome. By integrating insights from ophthalmology, otolaryngology, and related fields, the review seeks to identify gaps in current knowledge and propose areas for future research. Methods: A comprehensive search of peer-reviewed articles was conducted across multiple databases, focusing on studies related to the ocular and nasal involvement in Sjögren's Syndrome. Keywords included "Sjögren's Syndrome," "ocular involvement," "nasal involvement," "dry eye," "rhinitis," and "cross-specialty analysis." Studies were selected based on their relevance to the topic, and data were extracted and analyzed using a cross-specialty approach to identify common patterns, trends, and gaps in the literature. Results: The review highlights the interconnected pathophysiological mechanisms underlying ocular and nasal symptoms in Sjögren's Syndrome, emphasizing the importance of a multidisciplinary approach in diagnosis and treatment. Key findings include the identification of shared inflammatory pathways that contribute to both dry eye and nasal dryness, the role of autoimmunity in these processes, and the limitations of current diagnostic and treatment strategies when approached in isolation. The review also uncovered novel insights from comparing literature across specialties, revealing opportunities for more integrated care models. Conclusion: This cross-specialty literature review underscores the necessity of a holistic approach in both research and clinical practice for managing Sjögren's Syndrome. By bridging the gaps between specialties, the review contributes to a more comprehensive understanding of the disease, paving the way for more effective and integrated treatment strategies that address the full spectrum of its manifestations. Future research should focus on developing multidisciplinary diagnostic and therapeutic protocols to improve patient outcomes and quality of life.