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Occurrence of tuberculosis in anti-HIV positive patients between 2010 and 2020 in Brazil A systematic review

Objectives: To carry out a literature review on the occurrence of co-infected patients with tuberculosis and anti-HIV positive in the period from 2010 to 2020 in Brazil. Methodology: This study is a literature review, using the bibliographic databases MEDLINE, PUBMED, SciELO and BVSalud, with the keywords “tuberculosis”, “anti-HIV”, “prevalence”. Studies from controlled and randomized clinical trials, observational, systematic reviews, and meta-analysis were selected. The inclusion criteria used were the date of publication, between 2010 and 2020, types of study and language. Inclusion criteria were applied freely and independently by two reviewers. Results: TB-HIV co-infection is common but extremely harmful. The populations most prone to TB infection are males, indigenous people, people deprived of liberty, people living with the human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS), homeless people and health professionals. The diagnosis is based on clinical anamnesis and physical examination, radiological, bronchoscopic and laboratory tests and ADA dosage. The treatment must be carried out concomitantly in order to establish the therapeutic goal. Conclusion: The treatment of TB-HIV co-infection must be done concomitantly to obtain an effective cure combined with the adoption of public policies aimed at reducing vulnerable environments that predispose to co-infection.

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Occurrence of tuberculosis in anti-HIV positive patients between 2010 and 2020 in Brazil A systematic review

  • DOI: 10.22533/at.ed.1593402301061

  • Palavras-chave: "Tuberculosis"; “Anti-HIV”; “Prevalence”.

  • Keywords: "Tuberculosis"; “Anti-HIV”; “Prevalence”.

  • Abstract:

    Objectives: To carry out a literature review on the occurrence of co-infected patients with tuberculosis and anti-HIV positive in the period from 2010 to 2020 in Brazil. Methodology: This study is a literature review, using the bibliographic databases MEDLINE, PUBMED, SciELO and BVSalud, with the keywords “tuberculosis”, “anti-HIV”, “prevalence”. Studies from controlled and randomized clinical trials, observational, systematic reviews, and meta-analysis were selected. The inclusion criteria used were the date of publication, between 2010 and 2020, types of study and language. Inclusion criteria were applied freely and independently by two reviewers. Results: TB-HIV co-infection is common but extremely harmful. The populations most prone to TB infection are males, indigenous people, people deprived of liberty, people living with the human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS), homeless people and health professionals. The diagnosis is based on clinical anamnesis and physical examination, radiological, bronchoscopic and laboratory tests and ADA dosage. The treatment must be carried out concomitantly in order to establish the therapeutic goal. Conclusion: The treatment of TB-HIV co-infection must be done concomitantly to obtain an effective cure combined with the adoption of public policies aimed at reducing vulnerable environments that predispose to co-infection.

  • Leonardo Bueno Mesquita dos Santos
  • Beatriz Pinel Bernardo Leon Pereira
  • Salma Beatriz Barbosa Cadena de Freitas 
  • Ricardo Toshio Enohi 
  • Lourdes Conceição Martins
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