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THE POTENTIAL OF OZONE THERAPY IN RELIEVING CHRONIC PAIN: AN UPDATED REVIEW

OBJECTIVE: To explore and analyze the most recent and relevant studies that address the potential of ozone therapy in relieving chronic pain.  
METHODS: We used the SciELO and PubMed databases, using the following search strategy: "Ozone Therapy" AND "Chronic Pain", to carry out this literature review. We included articles in English or Portuguese, published in the last 5 years, and studies relating the application of ozone therapy to chronic pain. 69 articles were found, of which 18 were selected for this study. 
RESULTS: The results obtained reinforce the growing relevance of ozone therapy as a therapeutic option in various conditions associated with chronic pain, whether in the context of joint diseases, fibromyalgia, low back pain or other musculoskeletal injuries. This is related to ozone's ability to modulate inflammatory processes, induce oxidative stress and ultimately promote tissue regeneration. 
CONCLUSION: This study demonstrates that ozone therapy is an effective resource in the management of chronic pain, especially in rheumatological complaints, since it will provide an anti-inflammatory effect and reduce oxidative stress, resulting in pain relief in the short and medium term. However, more studies are needed to develop a safe protocol for the use of ozone therapy in chronic pain.

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THE POTENTIAL OF OZONE THERAPY IN RELIEVING CHRONIC PAIN: AN UPDATED REVIEW

  • DOI: https://doi.org/10.22533/at.ed.159532509017

  • Palavras-chave: Ozone therapy; Chronic pain; Knee osteoarthritis; Low back pain.

  • Keywords: Ozone therapy; Chronic pain; Knee osteoarthritis; Low back pain.

  • Abstract:

    OBJECTIVE: To explore and analyze the most recent and relevant studies that address the potential of ozone therapy in relieving chronic pain.  
    METHODS: We used the SciELO and PubMed databases, using the following search strategy: "Ozone Therapy" AND "Chronic Pain", to carry out this literature review. We included articles in English or Portuguese, published in the last 5 years, and studies relating the application of ozone therapy to chronic pain. 69 articles were found, of which 18 were selected for this study. 
    RESULTS: The results obtained reinforce the growing relevance of ozone therapy as a therapeutic option in various conditions associated with chronic pain, whether in the context of joint diseases, fibromyalgia, low back pain or other musculoskeletal injuries. This is related to ozone's ability to modulate inflammatory processes, induce oxidative stress and ultimately promote tissue regeneration. 
    CONCLUSION: This study demonstrates that ozone therapy is an effective resource in the management of chronic pain, especially in rheumatological complaints, since it will provide an anti-inflammatory effect and reduce oxidative stress, resulting in pain relief in the short and medium term. However, more studies are needed to develop a safe protocol for the use of ozone therapy in chronic pain.

  • Laura Beatriz Morais Leite
  • Marianna Pereira Silva Ramalho
  • Cecília Maria Tavares Machado
  • Clarisse Cleide Fagundes Siqueira Chaves
  • Giovana Nunes de Assunção
  • Laura Isabel Duarte de Santana
  • Taís Holland Queiroz
  • Raquel Pereira de Lima
  • Valeska Cristina Bulhões de Souza
  • Ricardo Ney Cobucci
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