THE ROLE OF INFLAMMATION IN ATHEROSCLEROSIS AND IMPLICATIONS FOR HEART TREATMENT

• DOI: 10.22533/at.ed.1593662329088

• Palavras-chave: Atherosclerosis. Cardiovascular risk. anti-inflammatory therapy.

• Keywords: Atherosclerosis. Cardiovascular risk. anti-inflammatory therapy.

• Abstract:

  Atherosclerosis, a chronic disease characterized by the accumulation of plaque on arterial walls, is driven by complex inflammatory processes. Inflammation plays a central role from endothelial injury to the formation of atherosclerotic plaques. Inflammatory cells such as monocytes and macrophages trigger the inflammatory cascade, releasing cytokines and adhesion molecules that perpetuate the inflammatory response and promote the progression of atherosclerosis. This understanding has led to the development of new therapeutic strategies, including the use of anti-inflammatory therapies to modulate inflammation and reduce cardiovascular risk. Implications for cardiac treatment include the use of inflammatory cytokine inhibitors and other therapies aimed at modulating the inflammatory response as an integral part of treatment plans. The multifactorial, personalized approach to the prevention and treatment of cardiovascular disease now considers inflammation as a significant therapeutic target, providing a new perspective on cardiac care.