O papel da Endoscopia Digestiva Alta nos portadores de Doença Renal Crônica Dialítica
O papel da Endoscopia Digestiva Alta nos portadores de Doença Renal Crônica Dialítica
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DOI: https://doi.org/10.22533/at.ed.8208242610024
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Palavras-chave: Doença Renal Crônica; Achados endoscópicos; Achados anatomopatológicos; Helicobacter pylori.
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Keywords: Chronic Kidney Disease; Endoscopic findings; Histopathological findings; Helicobacter pylori.
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Abstract: Introduction: Chronic Kidney Disease (CKD) is associated with systemic inflammation and an increased risk of gastrointestinal complications, including premalignant lesions and cancer. In dialysis-dependent CKD, gastric mucosal abnormalities and Helicobacter pylori (HP) infection are common. Objectives: To describe endoscopic and histopathological findings of the gastric mucosa and to evaluate the prevalence of HP infection in dialysis-dependent CKD. Methods: A cross-sectional, descriptive, retrospective study evaluating individuals followed at the nephrology outpatient clinic of Walter Cantídio University Hospital who underwent upper gastrointestinal endoscopy (EGD) with gastric biopsy between 2019 and 2024. Results: A total of 148 patients were included, predominantly male (57%) and aged ≥50 years (59%). Gastritis was the most frequent endoscopic finding (80%). Atrophy, metaplasia, gastric ulcer, and polyps were infrequent. HP infection was observed in 29% of patients. Conclusion: HP infection showed a moderate prevalence. Premalignant and neoplastic lesions, although infrequent, play an important role in screening in order to achieve a favorable prognosis through early diagnosis. The discrepancy between endoscopic and histopathological findings highlights the importance of systematic biopsy. Therefore, performing EGD with biopsy proves to be a valuable tool for early diagnosis, risk stratification, and appropriate management of gastrointestinal complications in CKD.
- Marcelo Veras Tavares
- Michelle Melo Candido Aires
- Fred Olavo Aragão Carneiro Andrade
- Antonio Brazil Viana Junior
- Amanda Pereira Sindeaux Pinheiro
- Gabriel Moreira de Lima Ramos
- Mateus Inocêncio Ferreira de Sena
- Vitor de Sousa Tomé