Necrolytic migratory erythema as a diagnostic clue: A rare report of glucagonoma.

• DOI: https://doi.org/10.22533/at.ed.1595332520113

• Palavras-chave: tumor neuroendócrino, glucagonoma, tumor pancreático

• Keywords: neuroendocrine tumor, glucagonoma, pancreatic tumor.

• Abstract: Introduction: Glucagonomas are pancreatic neuroendocrine tumors that arise from well-differentiated neuroendocrine cells in the pancreatic islets. They are considered harmful neoplasms and are commonly small in size due to their endocrine excretion. Case Report: We present a case of a glucagonoma whose initial symptoms included necrolytic migratory erythema, hyperglycemia, weight loss, lethargy, a mass in the pancreatic tail, and thrombosis in the left common iliac vein. Specifically, a confounding factor was identified as a focus of endometriosis in the abdominal wall. The pancreatic mass was resected, and two years after surgery, the patient presents with good clinical and laboratory evolution. Conclusion: Glucagonoma is a rare pancreatic neuroendocrine tumor with significant malignant potential and difficult diagnosis.