GASTRIC LYMPHOMA IN A DOG: CASE REPORT

• DOI: 10.22533/at.ed.9733132324083

• Palavras-chave: Leukemia. Neoplasm. Canine. Stomach. Wisconsin-Madison.

• Keywords: Leukemia. Neoplasm. Canine. Stomach. Wisconsin-Madison.

• Abstract:

  Lymphoma is a malignant lymphoid neoplasm, originating from hematopoietic cells, of rapid and aggressive evolution, which mainly affects the lymph nodes and other solid visceral organs, such as the liver, spleen, stomach and intestine. Gastric neoplasms represent less than 1% of all canine tumors and have a higher prevalence in males. Alimentary lymphoma is a malignant tumor, characterized by neoplastic involvement of the gastrointestinal tract, mainly the stomach and small intestine and/or the mesenteric lymph nodes. Most clinical signs are nonspecific. The diagnosis of lymphoma is based on anamnesis, complete physical examination, complementary tests, tissue diagnosis and clinical staging. Cytological examination is important, however histopathological examination is recommended as it is conclusive. Contrast-enhanced X-ray and endoscopy are the methods of choice in the diagnosis of alimentary lymphoma. There are numerous chemotherapy protocols that act against lymphoma. The Winconsin-Madison chemotherapy protocol presents excellent results, as most dogs present good remission of the clinical condition. This protocol is formed by L-asparaginase, vincristine, cyclophosphamide, Methotrexate and doxorubicin. Despite being a disease that has no cure, it provides good quality of life and has a high percentage of complete, temporary remissions. Some factors are of great importance for determining the prognosis and helping to choose the protocol, such as clinical staging, anatomical location of the tumor, histological classification, mitotic index, presence of hormone receptors, initial response to chemotherapy, presence of paraneoplastic syndromes, invasiveness, immunophenotyping, age, species, breed and sex of the animal. The objective of this work is to report a clinical case of a young dog diagnosed with gastric lymphoma and treated with an adaptation of the Winconsin-Madison chemotherapy protocol.