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LEUKEMOID REACTION ASSOCIATED WITH CANINE LEPTOSPIROSIS

Leptospirosis is a zoonosis with worldwide distribution, mainly in tropical regions. It is usually transmitted by direct contact of the skin and mucous membranes with urine, blood, and other organic fluids, contaminated from infected animals. Clinically it is a polymorphic disease that can be confused with multiple infectious diseases and can cause hematological alterations that can show a leukemoid reaction. The objective of the present work is to describe the association of the Leukemoid Reaction in the course of canine leptospirosis. Methodology: 29 canine patients with leptospirosis were analyzed who, in the course of disease progression, developed a leukemoid reaction with a leukocyte count between 25,000/50,000 cells/μl and reactive hyperplastic bone marrow cytology. After the initiation of antibiotic treatment, the leukocyte count returned to normal, with a favorable clinical evolution. Conclusion: Extreme leukocytosis or leukemoid reaction should be considered during canine leptospirosis, for timely management and favorable clinical evolution of the patient.

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LEUKEMOID REACTION ASSOCIATED WITH CANINE LEPTOSPIROSIS

  • DOI: 10.22533/at.ed.973342312042

  • Palavras-chave: leptospirosis; canine, leukemoid reaction; zoonosis

  • Keywords: leptospirosis; canine, leukemoid reaction; zoonosis

  • Abstract:

    Leptospirosis is a zoonosis with worldwide distribution, mainly in tropical regions. It is usually transmitted by direct contact of the skin and mucous membranes with urine, blood, and other organic fluids, contaminated from infected animals. Clinically it is a polymorphic disease that can be confused with multiple infectious diseases and can cause hematological alterations that can show a leukemoid reaction. The objective of the present work is to describe the association of the Leukemoid Reaction in the course of canine leptospirosis. Methodology: 29 canine patients with leptospirosis were analyzed who, in the course of disease progression, developed a leukemoid reaction with a leukocyte count between 25,000/50,000 cells/μl and reactive hyperplastic bone marrow cytology. After the initiation of antibiotic treatment, the leukocyte count returned to normal, with a favorable clinical evolution. Conclusion: Extreme leukocytosis or leukemoid reaction should be considered during canine leptospirosis, for timely management and favorable clinical evolution of the patient.

  • Majo Tintel
  • María José Tintel Astigarraga
  • Romina Isabel Marini Benítez
  • Jorge Ramón Rivas Franco
  • Guillermo José Brown Beckelmann
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