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EVIDENCE-BASED INTERVENTIONS FOR TOURETTE SYNDROME: AN UPDATED REVIEW OF PHARMACOLOGICAL, BEHAVIORAL AND NON-PHARMACOLOGICAL THERAPIES

Objective: To describe therapeutic interventions for the treatment of TS, covering both pharmacological and non-pharmacological approaches. The aim is to identify the most effective interventions in reducing tics and improving patients' quality of life. Methodology: Literature review in the PubMed database. After applying the inclusion criteria, 25 articles were selected to compose the study. The review was conducted based on the PVO strategy, which involved analyzing the population or research problem, the variables involved and the expected outcome. Results: Pharmacological interventions, especially those that act on the dopaminergic system, proved to be effective in reducing tics in the short term. However, non-pharmacological treatment has gained prominence due to the side effects associated with drug interventions. It is up to the doctor and the patient to identify the most appropriate approach for each case, considering the advantages and disadvantages of each treatment. Final considerations: Both non-pharmacological and pharmacological treatment are effective in managing TS. However, some patients may not show satisfactory progress with these interventions, especially deep brain stimulation.

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EVIDENCE-BASED INTERVENTIONS FOR TOURETTE SYNDROME: AN UPDATED REVIEW OF PHARMACOLOGICAL, BEHAVIORAL AND NON-PHARMACOLOGICAL THERAPIES

  • DOI: 10.22533/at.ed.15934823300610

  • Palavras-chave: Tourette's Syndrome, Pharmacological Treatment, Non-Pharmacological Treatment, Deep Brain Stimulation.

  • Keywords: Tourette's Syndrome, Pharmacological Treatment, Non-Pharmacological Treatment, Deep Brain Stimulation.

  • Abstract:

    Objective: To describe therapeutic interventions for the treatment of TS, covering both pharmacological and non-pharmacological approaches. The aim is to identify the most effective interventions in reducing tics and improving patients' quality of life. Methodology: Literature review in the PubMed database. After applying the inclusion criteria, 25 articles were selected to compose the study. The review was conducted based on the PVO strategy, which involved analyzing the population or research problem, the variables involved and the expected outcome. Results: Pharmacological interventions, especially those that act on the dopaminergic system, proved to be effective in reducing tics in the short term. However, non-pharmacological treatment has gained prominence due to the side effects associated with drug interventions. It is up to the doctor and the patient to identify the most appropriate approach for each case, considering the advantages and disadvantages of each treatment. Final considerations: Both non-pharmacological and pharmacological treatment are effective in managing TS. However, some patients may not show satisfactory progress with these interventions, especially deep brain stimulation.

  • Amanda Franzoi Motter
  • Rafaela Goulart Cruz de Magalhães
  • Milena Kelner
  • Silvia Jordania Barboza da Silva
  • Sophia Bridi Zamprogno
  • Luiza Preato Machado
  • Lara Gonçalves de Moraes Bolzan
  • Karina Gil Tomaz Rolo
  • Clarice Carmona Ferreira
  • Thainá Catão Lopes
  • Natália de Souza Alvarenga Barbosa
  • Myrna Silveira
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