IMPACTS OF PHYSICAL EXERCISE ON THE REGENERATION OF MUSCLE STEM CELLS

• DOI: https://doi.org/10.22533/at.ed.1594292420031

• Palavras-chave: exercise, stem cell, regeneration, muscle

• Keywords: exercise, stem cell, regeneration, muscle

• Abstract:

  This review aimed to explore and analyze recent studies on the impacts of physical exercise on the regeneration of muscle stem cells and the effects on the health of these cells. For the research, different databases were used from 2015 to 2022, with the following indexing terms: “muscle cells”, “stem cells”, “physical exercises”, “muscle regeneration” and “impact of exercises”. Stem cells have a high capacity for regeneration and differentiate into specialized cells to promote cellular repair. Furthermore, the impacts of these cells on skeletal muscle tissue have received relevant attention in studies, being considered essential for the process, as they interact with several other regulatory pathways. Despite this, muscle regeneration also depends on a series of other interactions and mechanisms. When analyzing the relationship between muscle regeneration and exercise, physical activity can maintain muscle health and promote the proliferation of stem cells, as well as their rejuvenation, mainly in effect with resistance exercises, which promote the self-renewal of satellite cells. In conclusion, physical activity has a positive impact on the regeneration of muscle stem cells, however, strategies regarding exercise intensity and the mechanisms that specifically interfere with this process need to be better elucidated.