IMPACT OF PERIODONTAL TREATMENT ON CARDIOVASCULAR INFLAMMATORY MARKERS

• DOI: https://doi.org/10.22533/at.ed.1317632627035

• Palavras-chave: periodontitis; periodontal therapy; ultrasensitive C-reactive protein; interleukin-6; TNF-α.

• Keywords: periodontitis; periodontal therapy; ultrasensitive C-reactive protein; interleukin-6; TNF-α.

• Abstract:

  Periodontitis causes low-grade systemic inflammation with vascular repercussions. This review analyzes clinical trials and quantitative syntheses on the effect of periodontal treatment on cardiovascular biomarkers. A consistent reduction in ultrasensitive C-reactive protein is observed, with concomitant decreases in IL-6 and TNF-α, which are more pronounced when decontamination is intensive. In patients with high cardiometabolic risk, the response tends to be greater; in heart patients, quadrant execution offers a better safety margin. There are favorable signs in intermediate vascular outcomes (endothelial function and carotid intima-media thickness), although with heterogeneity between territories and clinical profiles. Integration of periodontal care into cardiovascular risk management is plausible and feasible, but further studies are needed to confirm the impact on clinical events.