IMPACT OF PROBIOTIC SUPPLEMENTATION ON ROSACEA: AN INTEGRATIVE REVIEW

• DOI: https://doi.org/10.22533/at.ed.1594922414107

• Palavras-chave: Probiotics. Rosacea. Dermatology. Skin Diseases. Cosmetic Microbiology.

• Keywords: Probiotics. Rosacea. Dermatology. Skin Diseases. Cosmetic Microbiology.

• Abstract:

  Introduction: Rosacea is a chronic, complex inflammatory disease with varied manifestations and an unclear etiology. Its treatment is varied and includes both oral and topical therapies that target symptoms and exacerbations. Objective: To understand the effects of using probiotic supplementation in patients affected by rosacea based on published scientific evidence and to discuss its mechanism of action. Method: An advanced search was carried out on the Virtual Health Library (VHL) and PubMed platforms. To optimize the results, the search included a Boolean operator and standardized descriptors using the Descriptors in Health Sciences (DeCS/MeSH). The inclusion criteria were full texts, free of charge and in Portuguese, English or Spanish that aligned with the research question. As an exclusion criterion, duplicate articles and those whose full text did not answer the guiding question were eliminated. Four articles were included in this review. Results: 13 different bacteria with applications in rosacea were mentioned. In terms of prevalence, the strains Bifidobacterium breve BR03, Lactobacillus salivarius LS01 and Vitreoscilla filiformis were widely linked to positive disease outcomes. The effect of using probiotics on the skin seems to favor the skin barrier – restoring its hydration, modulating the natural microbiota and reducing inflammatory cytokines. Conclusion: Although the use of probiotic strains has received favorable reviews, studies targeting rosacea are still scarce. The quality, quantity and formulation are not a consensus, although their use is already widespread by some dermocosmetic companies in diseases such as atopic dermatitis, psoriasis and acne.