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IMPACT OF BRAIN STIMULATION DEEP ON QUALITY OF LIFE AND MOOD IN PATIENTS WITH PARKINSON'S DISEASE

Parkinson's disease (PD) is a neurodegenerative disease resulting from a reduction in dopamine production. Its treatment is basically by pharmacological measures. However, we are
advanced stages of the disease, especially due to fluctuations in the
engine, pharmacological treatment alone is not completely successful. Thus, the possibility of benefits to the patient by the technique of deep brain stimulation (DBS) arises. The aim of this study was to analyze the impact of pallidal or subthalamic DBS on these patients' quality of life (QoL). For that, two scales were used, comparing the pre- and postoperative results: the Beck Depression Inventory - BDI (evaluates the emotional aspect of the patients) and the PDQ-39 (evaluates the motor aspects and the social relationships). We can observe that the BDI assessment pointed to an average improvement of 9.5% and the PDQ-39 scores improved by 10.28%. There is evidence that patients submitted to the subalamic or palliative DBS technique showed a significant QoL improvement, thus, DBS appears as an adjuvant in the fight against Parkinson's disease.

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IMPACT OF BRAIN STIMULATION DEEP ON QUALITY OF LIFE AND MOOD IN PATIENTS WITH PARKINSON'S DISEASE

  • DOI: 10.22533/at.ed.159342302016

  • Palavras-chave: Estimulação cerebral profunda, doença de Parkin- son, Depressão, Qualidade de vida.

  • Keywords: Deep Brain Stimulation, Parkinson´s disease, Depression, Quality of life.

  • Abstract:

    Parkinson's disease (PD) is a neurodegenerative disease resulting from a reduction in dopamine production. Its treatment is basically by pharmacological measures. However, we are
    advanced stages of the disease, especially due to fluctuations in the
    engine, pharmacological treatment alone is not completely successful. Thus, the possibility of benefits to the patient by the technique of deep brain stimulation (DBS) arises. The aim of this study was to analyze the impact of pallidal or subthalamic DBS on these patients' quality of life (QoL). For that, two scales were used, comparing the pre- and postoperative results: the Beck Depression Inventory - BDI (evaluates the emotional aspect of the patients) and the PDQ-39 (evaluates the motor aspects and the social relationships). We can observe that the BDI assessment pointed to an average improvement of 9.5% and the PDQ-39 scores improved by 10.28%. There is evidence that patients submitted to the subalamic or palliative DBS technique showed a significant QoL improvement, thus, DBS appears as an adjuvant in the fight against Parkinson's disease.

  • Gabriel Alves
  • Lorena Broseghini Barcelos
  • Vanderci Borges
  • Ricardo Silva Centeno
  • Henrique Ballalai Ferraz
  • Murilo Martinez Marine
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