IMPACT OF SGLT2 INHIBITORS ON HEART FAILURE
Heart failure (HF) affects up to more than 20% of patients with type 2 diabetes (DM2), even more in the elderly. Finally, the updated clinical evidence of the benefits of SGLT2i in HF was summarized. Thus, this review aimed to analyze the cardioprotective mechanisms of glucose transporter sodium 2 inhibitors (SGLT2i) in patients with HF, as well as their clinical impact on cardiovascular events. to intracellular sodium-reducing molecules. This provides its consequent cardioprotective effect, which justifies its significant reduction in CV events, especially in higher-risk populations.
IMPACT OF SGLT2 INHIBITORS ON HEART FAILURE
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DOI: 10.22533/at.ed.1592202218048
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Palavras-chave: SGLT2 inhibitors, heart failure, pathophysiology, type 2 diabetes, cardiovascular risk
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Keywords: SGLT2 inhibitors, heart failure, pathophysiology, type 2 diabetes, cardiovascular risk
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Abstract:
Heart failure (HF) affects up to more than 20% of patients with type 2 diabetes (DM2), even more in the elderly. Finally, the updated clinical evidence of the benefits of SGLT2i in HF was summarized. Thus, this review aimed to analyze the cardioprotective mechanisms of glucose transporter sodium 2 inhibitors (SGLT2i) in patients with HF, as well as their clinical impact on cardiovascular events. to intracellular sodium-reducing molecules. This provides its consequent cardioprotective effect, which justifies its significant reduction in CV events, especially in higher-risk populations.
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Número de páginas: 7
- Marco Antônio Netto Armando Rangel
- Matheus Marques da Costa
- Pollini Pereira de Moraes
- Thaís Baroni Azzi
- Ana Carolina Alves da Conceição
- Ana Carolina Moraes Mattos
- Thaynara Alves de Souza Maciel
- Andre Luis Yamamoto Nose
- Thainá Pereira de Moraes
- Kívia da Silva Joia
- Rodrigo Netto Armando Rangel
- Patrick de Abreu Cunha Lopes
