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JAUNDICE DUE TO MATERNOFETAL INCOMPATIBILITY: CASE REPORT

Jaundice is the clinical manifestation of hyperbilirubinemia, with yellowing of the skin, sclera and mucous membranes. Through careful anamnesis and physical examination, it is possible to identify risk factors for evolution with hyperbilirubinemia and its gold standard diagnosis is made through the measurement of total bilirubin and fractions in the blood. That said, the hemolytic disease of the newborn is the main etiology of pathological jaundice, being associated with the presence of maternal autoantibodies that react against red blood cells of the newborn, with phototherapy being the most indicated intervention and, in some more specific cases, the exchange transfusion. 

Goal: To report the necessary conducts in the face of a serious case of maternal-fetal incompatibility. Discussion: Since jaundice is a disease that can evolve seriously, essential measures at birth are discussed to better manage the case, with an assessment of the need for rigorous bilirubin collection, and even the possibility of indicating exchange transfusion. 

Conclusion: It is evident that the investigation of the maternal history of previous pregnancies is extremely important to assist in directing the approach to newborns at high risk for the development of severe hyperbilirubinemia.
 

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JAUNDICE DUE TO MATERNOFETAL INCOMPATIBILITY: CASE REPORT

  • DOI: 10.22533/at.ed.1593662329089

  • Palavras-chave: Jaundice. Erythroblastosis fetalis. Hemolysis.

  • Keywords: Jaundice. Erythroblastosis fetalis. Hemolysis.

  • Abstract:

    Jaundice is the clinical manifestation of hyperbilirubinemia, with yellowing of the skin, sclera and mucous membranes. Through careful anamnesis and physical examination, it is possible to identify risk factors for evolution with hyperbilirubinemia and its gold standard diagnosis is made through the measurement of total bilirubin and fractions in the blood. That said, the hemolytic disease of the newborn is the main etiology of pathological jaundice, being associated with the presence of maternal autoantibodies that react against red blood cells of the newborn, with phototherapy being the most indicated intervention and, in some more specific cases, the exchange transfusion. 

    Goal: To report the necessary conducts in the face of a serious case of maternal-fetal incompatibility. Discussion: Since jaundice is a disease that can evolve seriously, essential measures at birth are discussed to better manage the case, with an assessment of the need for rigorous bilirubin collection, and even the possibility of indicating exchange transfusion. 

    Conclusion: It is evident that the investigation of the maternal history of previous pregnancies is extremely important to assist in directing the approach to newborns at high risk for the development of severe hyperbilirubinemia.
     

  • Stephanie Marie Oliveira de Mendonça
  • Ana Carla Cunha Gravina
  • Beatriz Dypeu Barboza Rodrigues da Rosa
  • Ellen Cunha Noel
  • Juliana Brum de Souza Almeida
  • Lara Alencar Franco de Mattos
  • Luiza Almeida Marin Munhoz
  • Maria Oliveira Thiébaut
  • Mariana Oliveira Klein
  • Natália Assis Massa
  • Taís Monte Real Raña
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