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HORMONE REPLACEMENT THERAPIES IN MENOPAUSE

Objective: To evaluate the databases on climacteric symptoms and the positive and negative effects of menopausal hormone therapy. Methods: An integrative review was carried out, using as criteria the search in the National Library of Medicine (PubMed) and Scientific Electronic Library Online (SciELO) databases using the descriptors (i) climacteric (ii) hormone replacement (iii) menopause, with the Boolean operator “AND”. Studies published from 2020 to 2024 were included. Results: Among the benefits of hormone therapy are improved sleep, mood disorders, reduced insulin resistance, reduced risk of dementia, improved quality of life, and prevention of cardiovascular diseases when started within the window of opportunity. It must be noted that there are negative points in carrying out hormone replacement therapy, such as an increased risk of gynecological neoplasms, increased liver complications, in addition to there being numerous contraindications to its use. Final considerations: It is known that the benefits of HRT outweigh the risks as long as it is well indicated, within the therapeutic window for its initiation, and respecting the contraindications to the use of the therapy. The improvement in quality of life, sexual practice and years lived in this phase become less difficult with the correct implementation of hormone replacement therapy, thus providing support so that women can get through this phase in the best possible way.

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HORMONE REPLACEMENT THERAPIES IN MENOPAUSE

  • DOI: https://doi.org/10.22533/at.ed.1594802427082

  • Palavras-chave: climacteric, hormone replacement therapy and menopause.

  • Keywords: climacteric, hormone replacement therapy and menopause.

  • Abstract:

    Objective: To evaluate the databases on climacteric symptoms and the positive and negative effects of menopausal hormone therapy. Methods: An integrative review was carried out, using as criteria the search in the National Library of Medicine (PubMed) and Scientific Electronic Library Online (SciELO) databases using the descriptors (i) climacteric (ii) hormone replacement (iii) menopause, with the Boolean operator “AND”. Studies published from 2020 to 2024 were included. Results: Among the benefits of hormone therapy are improved sleep, mood disorders, reduced insulin resistance, reduced risk of dementia, improved quality of life, and prevention of cardiovascular diseases when started within the window of opportunity. It must be noted that there are negative points in carrying out hormone replacement therapy, such as an increased risk of gynecological neoplasms, increased liver complications, in addition to there being numerous contraindications to its use. Final considerations: It is known that the benefits of HRT outweigh the risks as long as it is well indicated, within the therapeutic window for its initiation, and respecting the contraindications to the use of the therapy. The improvement in quality of life, sexual practice and years lived in this phase become less difficult with the correct implementation of hormone replacement therapy, thus providing support so that women can get through this phase in the best possible way.

  • Amanda Lima Souza
  • Anacleto Fernando Liporaci Hilário
  • Guillermo Gonçalves Diana
  • Gabriel Pereira Cardoso
  • Caiohan Dalfiôr
  • Gustavo Vasconcelos Ribeiro
  • Thállita Gabriela Freitas Ferreira
  • Gustavo André Tabalipa
  • Taisnara Martins Oliveira
  • Victória Flávia Vieira Rodrigues
  • Mailine Mara Silva Maroso
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