The placenta is a highly specialized organ responsible for transporting nutrients and metabolic waste from the mother to the fetus. Adequate placentation is essential for normal embryonic development and poor placental development is associated with several complications of pregnancy, such as preeclampsia. In addition, the pandemic caused by the new acute respiratory syndrome coronavirus 2 (SARS-CoV-2), demonstrated a strong relationship with the risk of miscarriage, increased incidence of preeclampsia, stillbirths and prematurity. The role of COVID-19 as a risk factor for preeclampsia is still controversial. The main reports point out that preeclampsia is associated with severe cases of COVID-19, but is not present in mild or moderate cases of the disease. Future studies are needed to collect more robust data to further validate or substantiate these findings, better understand the pathophysiological pathways that explain these associations, and identify effective strategies to prevent adverse outcomes in pregnant women with COVID-19.

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DOI: 10.22533/at.ed.1592712216111
Palavras-chave: Placenta; Placentation; Placental diseases; Placental circulation.
Keywords: Placenta; Placentation; Placental diseases; Placental circulation.
Abstract:
The placenta is a highly specialized organ responsible for transporting nutrients and metabolic waste from the mother to the fetus. Adequate placentation is essential for normal embryonic development and poor placental development is associated with several complications of pregnancy, such as preeclampsia. In addition, the pandemic caused by the new acute respiratory syndrome coronavirus 2 (SARS-CoV-2), demonstrated a strong relationship with the risk of miscarriage, increased incidence of preeclampsia, stillbirths and prematurity. The role of COVID-19 as a risk factor for preeclampsia is still controversial. The main reports point out that preeclampsia is associated with severe cases of COVID-19, but is not present in mild or moderate cases of the disease. Future studies are needed to collect more robust data to further validate or substantiate these findings, better understand the pathophysiological pathways that explain these associations, and identify effective strategies to prevent adverse outcomes in pregnant women with COVID-19.

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