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HYPERTHYROIDISM AND PSEUDODEMENCE – LITERATURE REVIEW

Introduction: Thyroid hormones are essential for brain development. Disabilities due to lack of these often result in mental retardation (PRZYBYLAK M, et al., 2021). Goal: To review the relationship between hyperthyroidism and pseudodementia. Result: The dysfunctions in this scenario mainly refer to cognitive ones, but with less intensity when compared to hypothyroidism. Disorders frequently observed in studies include reduced performance on attention and memory tests, as well as disturbances in the synchronization of visual stimuli with motor activities, anxiety and mood disorders, including manic and depressive episodes. Thyroid overactivity can even lead to delusional states (PRZYBYLAK M, et al., 2021). These situations, which are sometimes reversible, are known as "pseudodementia" and highlight the importance of a thorough evaluation before diagnosing dementia. (Bégin ME, et al., 2008). Conclusion:  Hyperthyroidism is more prevalent in the elderly and is often associated with pre-existing cognitive impairment and, for this reason, organic causes must always be sought when there is a decline in mental functions.

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HYPERTHYROIDISM AND PSEUDODEMENCE – LITERATURE REVIEW

  • DOI: 10.22533/at.ed.1593822305101

  • Palavras-chave: Hyperthyroidism; Pseudodementia; Cognitive impairment.

  • Keywords: Hyperthyroidism; Pseudodementia; Cognitive impairment.

  • Abstract:

    Introduction: Thyroid hormones are essential for brain development. Disabilities due to lack of these often result in mental retardation (PRZYBYLAK M, et al., 2021). Goal: To review the relationship between hyperthyroidism and pseudodementia. Result: The dysfunctions in this scenario mainly refer to cognitive ones, but with less intensity when compared to hypothyroidism. Disorders frequently observed in studies include reduced performance on attention and memory tests, as well as disturbances in the synchronization of visual stimuli with motor activities, anxiety and mood disorders, including manic and depressive episodes. Thyroid overactivity can even lead to delusional states (PRZYBYLAK M, et al., 2021). These situations, which are sometimes reversible, are known as "pseudodementia" and highlight the importance of a thorough evaluation before diagnosing dementia. (Bégin ME, et al., 2008). Conclusion:  Hyperthyroidism is more prevalent in the elderly and is often associated with pre-existing cognitive impairment and, for this reason, organic causes must always be sought when there is a decline in mental functions.

  • Maria Clara Dias Coelho Menezes
  • Tiago Muniz Vieira de Melo
  • Marcela Maria Buarque de Macedo Gadelha
  • Luiz Gustavo Vieira Gonçalves
  • Samanttha Cristina da Silva Chaves
  • Paula Eduarda Dalmaz Boaretto
  • Carlos Alberto Mendonça Filho
  • Rafael Amorim Jambo Cantarelli
  • Leonardo William Braga de Araújo
  • Matheus Henrique Santos Lira Oliveira
  • Anny Izumi Toma
  • Marta de Souza Silva
  • Jéssika Mylleny Xavier Dos Santos
  • Maria Eduarda da Motta Fernandes Pagnoncelli
  • Giovanna Ferreira Lopes
  • Stephânia Taveira Maximiano Cerqueira
  • Adriano de Lucena Jambo Cantarelli
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