HEPATOBLASTOMA PRODUCING HUMAN CHORIONIC BETA GONADROTOPIN (B-HCG): A CASE REPORT

• DOI: 10.22533/at.ed.1593102307021

• Palavras-chave: Hepatoblastoma. Alphafetoprotein. B-hCG.

• Keywords: Hepatoblastoma. Alphafetoprotein. B-hCG.

• Abstract:

  Introduction: Hepatoblastoma (HB) is the most common liver tumor in infants and children. It is responsible for more than 90% of malignant liver tumors among children under 5 years of age. HB, in most cases, is associated with an increase in AFP, but there is another marker, human chorionic gonadrotophin beta (B-hCG), little described in the literature because its occurrence is rare, since only 18% of cases have it. a high level of B-hCG. Objective: To report the case of a patient diagnosed with hepatoblastoma who at the time of diagnosis had high serum levels of alpha-fetoprotein (AFP) and B-hCG. Description of case: This is a case in which a patient aged 1 year and 3 months was diagnosed with B-hCG-producing hepatoblastoma with high levels of AFP. He underwent preoperative chemotherapy, total tumor resection and postoperative chemotherapy and is in remission. Discussion: Clinically, hepatoblastoma appears similar to other liver tumors, with abdominal distention or a palpable abdominal mass, often associated with nonspecific symptoms such as the anorexia, pain, fatigue and weight loss. Since this is a rare case, it is very important to document new cases to enrich the literature on the subject.