EVIDENCE-BASED STRATEGIES TO OPTIMIZE ANTIBIOTIC PRESCRIBING AND COMBAT RESISTANCE

• DOI: https://doi.org/10.22533/at.ed.159542514018

• Palavras-chave: Antimicrobial resistance, Antibiotics, Medical prescription.

• Keywords: Antimicrobial resistance, Antibiotics, Medical prescription.

• Abstract:

  To identify and review effective evidence-based strategies that can be implemented to improve antibiotic prescribing practices and reduce the development of antimicrobial resistance. Methodology: Narrative literature review developed according to the criteria of the PVO strategy, using the PubMed database. The search terms included ''antibiotic stewardship'', ''antibiotic protocols'', ''antimicrobial stewardship'', ''evidence-based'', ''evidence-based guidelines'' and their combinations. After applying the inclusion and exclusion criteria, a total of 16 articles from 2019 to 2024 were selected. Review: Antimicrobial stewardship programs have shown great effectiveness in reducing the use of specific antibiotics, as well as highlighting the importance of training healthcare professionals to identify specific prescriptions. In addition, the use of rapid diagnostic technologies, such as biomarkers and rapid PCR tests, especially in emergency units, has proved essential for a more precise approach. Studies show that investments in rapid diagnostic infrastructure are offset by the reduction in costs associated with the treatment of infections, hospitalizations and complications arising from involved prescriptions. Final considerations: These actions promote the rational use of antimicrobials, improve clinical stages and control costs. However, limitations include specific research for the development of new drugs and lack of acceptance by health professionals and patients. Combating antimicrobial resistance (AMR) requires integrated efforts between the government, health professionals and society.