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DEEP BRAIN STIMULATION (DBS) IN PATIENTS WITH PARKINSON'S DISEASE: AN INTEGRATIVE REVIEW ON EFFECTIVENESS, INDICATIONS AND COMPLICATIONS

The objective of this integrative review is to present a critical and up-to-date analysis of the evidence available in the literature on the efficacy, indications and complications of the DBS procedure in patients with PD.Methodology: For this integrative review, the search was in indexed databases such as PubMed, Scopus and Web of Science, using a combination of keywords related to the terms "deep brain stimulation", "Parkinson's Disease" and their variations. Results: After the complete analysis, 8 studies that met the established inclusion criteria were included in the systematic review table. Based on the studies, DBS is an effective treatment option for patients with advanced Parkinson's disease who do not respond adequately to drug treatment. It can produce benefits by significantly reducing chronic pain, improving postural disorders and being an effective therapeutic option for patients with camptocormia related to Parkinson's disease. These results suggest that DBS may be an important treatment option for patients with advanced Parkinson's disease. Conclusion: DBS has been shown to be a promising alternative for the treatment of PD, especially for patients who can no longer control their symptoms with conventional medications. Research is needed to improve DBS techniques and evaluate the long-term benefits of deep brain stimulation in PD patients.

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DEEP BRAIN STIMULATION (DBS) IN PATIENTS WITH PARKINSON'S DISEASE: AN INTEGRATIVE REVIEW ON EFFECTIVENESS, INDICATIONS AND COMPLICATIONS

  • DOI: 10.22533/at.ed.1593402301063

  • Palavras-chave: Deep brain stimulation; Parkinson disease; Therapeutics.

  • Keywords: Deep brain stimulation; Parkinson disease; Therapeutics.

  • Abstract:

    The objective of this integrative review is to present a critical and up-to-date analysis of the evidence available in the literature on the efficacy, indications and complications of the DBS procedure in patients with PD.Methodology: For this integrative review, the search was in indexed databases such as PubMed, Scopus and Web of Science, using a combination of keywords related to the terms "deep brain stimulation", "Parkinson's Disease" and their variations. Results: After the complete analysis, 8 studies that met the established inclusion criteria were included in the systematic review table. Based on the studies, DBS is an effective treatment option for patients with advanced Parkinson's disease who do not respond adequately to drug treatment. It can produce benefits by significantly reducing chronic pain, improving postural disorders and being an effective therapeutic option for patients with camptocormia related to Parkinson's disease. These results suggest that DBS may be an important treatment option for patients with advanced Parkinson's disease. Conclusion: DBS has been shown to be a promising alternative for the treatment of PD, especially for patients who can no longer control their symptoms with conventional medications. Research is needed to improve DBS techniques and evaluate the long-term benefits of deep brain stimulation in PD patients.

  • Grasiele Mattei Ise dos Santos
  • Mariana Pirslhner Managna
  • Danielle Beltrão Araujo Mendes Amorim
  • Larissa Faria Reis
  • Claudia Suzana da Matta Pereira
  • Heuller Alexandre Marteline Bendia
  • Luana Amanda Antunes de Souza
  • Pedro Pereira de Medeiros
  • Eduarda Soares Sarmento da Costa
  • Thayná Vargas de Jesus Alves
  • Rafael Dias Moura Farias da Paixão
  • Vyctor de Almeida Fochat
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