EFFECT OF TEMPERATURE ON THE KINETICS OF ENZYMATIC HYDROLYSIS OF SARDINE OIL BY DIFFERENT LIPASES
EFFECT OF TEMPERATURE ON THE KINETICS OF ENZYMATIC HYDROLYSIS OF SARDINE OIL BY DIFFERENT LIPASES
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DOI: https://doi.org/10.22533/at.ed.813422408027
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Palavras-chave: hidrólisis, parámetros cinéticos, modelo reversible de Michaellis-Menten, actividad enzimática
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Keywords: hydrolysis, kinetic parameters, Michaelis-Menten reversible model, enzymatic activity
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Abstract: In the present work, the effect of temperature on the partial enzyme-catalysed hydrolysis of sardine oil by three different lipases was studied: Candida rugosa AY-30, Rhizopus oryzae FAP-15 and Burkoldheria cepacian PS-CI. The reaction was carried out in glass flasks containing an emulsion of sardine oil:phosphate buffer solution of pH 7.0 (40:60 v/v) and 0.05 g of the different enzymes. The resulting mixtures were placed on magnetic stirring plates inside of an incubator at 20, 30, 40, 50 and 60°C. Samples were withdrawn at different reaction times. To describe the global hydrolysis, a reversible Michaelis-Menten model was considered, which includes an "α-factor" that considers the loss of enzymatic activity due to thermal denaturing. PS-CI lipase exhibited both the greatest enzymatic activity and thermal stability, reaching a hydrolysis degree of 0.468 at 24 h. The kinetic parameters of the models were estimated by non-linear regression with restrictions in a MATLAB® platform (R2018b), with a coefficient of determination (Rprom2 >0.93).
- JUAN ANTONIO NORIEGA RODRÍGUEZ
- Christian Correa Leyva
- Esther Carrillo Pérez
- Abraham Rogelio Martin García
- Ramiro Baeza Jiménez