PERIANAL BOWEN DISEASE: an integrative review

• DOI: 10.22533/at.ed.1593592311088

• Palavras-chave: Bowen's Disease. Human papillomavirus. anogenital carcinoma.

• Keywords: Bowen's Disease. Human papillomavirus. anogenital carcinoma.

• Abstract:

  Bowen's disease can occur in different parts of the body, such as the head, hands and perianal region. Its morphology is that of an epithelial lesion with a dry appearance, irregular edges, red and scaly. When there are symptoms, it can present painful nodules, hemorrhage and eczema. It is predominantly due to infection with the human papillomavirus HPV types 16 and 6. These are most commonly responsible for persistent infection in the anogenital area, resulting in squamous cell carcinoma. The aim of the present work is to identify the most accurate diagnostic and treatment methods for perianal Bowen's disease. This is an integrative literature review, using 10 articles carefully selected from electronic databases: Scielo; Medline and Lilacs, complete original articles published and indexed in national and international journals in the languages: Portuguese, English and Spanish relevant to the subject studied, between January 2012 and January 2022. As a result, enabling the understanding that, in addition to the biopsy, which is the gold standard for the diagnosis of Bowen's disease, anal colposcopy and immunohistochemical examination can be excellent complementary methods. When it comes to treatment, excision is effective in reducing the recurrence of lesions, and photodynamic therapy presents recurrence in smaller foci. The highlighted information can conclude that there are current complementary methods for the diagnosis of Bowen's disease, and the importance of an individualized treatment, taking into consideration, the particularities of each patient.