Difficulties in the Social Interaction of Autistic Individuals: A Neuroscientific Perspective on the Interpretation and Manipulation of Emotions

• DOI: https://doi.org/10.22533/at.ed.1595122524028

• Palavras-chave: Autism Spectrum Disorder, Social Interaction, Neuroscience, Corpus Callosum, Amygdala, Insula, Anterior Cingulate Cortex, Superior Temporal Sulcus, Orbitofrontal Cortex, Fusiform Gyrus.

• Keywords: Autism Spectrum Disorder, Social Interaction, Neuroscience, Corpus Callosum, Amygdala, Insula, Anterior Cingulate Cortex, Superior Temporal Sulcus, Orbitofrontal Cortex, Fusiform Gyrus.

• Abstract:

  Autism Spectrum Disorder (ASD) is characterized by significant challenges in social interaction, often associated with difficulties in interpreting and manipulating emotions. This article reviews the neurobiological basis of these difficulties, focusing on critical brain regions such as the amygdala, corpus callosum, insula, anterior cingulate cortex, basal ganglia, fusiform gyrus, superior temporal sulcus, dorsolateral prefrontal cortex and orbitofrontal cortex. The integration of neuroimaging data, neurochemical studies and brain connectivity analyses offers a comprehensive view of the dysfunctions that contribute to social difficulties in ASD. The implications of these findings for therapeutic interventions and future research are discussed.