DEVELOPMENT AND PHYSICAL-CHEMICAL AND MORPHOLOGICAL CHARACTERIZATION OF NANOSTRUCTURES CONTAINING ETHANOLIC EXTRACT FROM SYZYIUM MALACCENSE (L.) MERR LEAVES. & L. M. PERRY WITH POTENTIAL PHOTOPROTECTIVE PURPOSE

• DOI: 10.22533/at.ed.3173402323115

• Palavras-chave: Syzygium malaccense. Photoprotection. Polymeric Nanoparticle.

• Keywords: Syzygium malaccense. Photoprotection. Polymeric Nanoparticle.

• Abstract:

  Solar radiation reaches the Earth's surface through rays, such as Ultraviolet (UV), which cause damage to health. Therefore, there is great demand for sunscreen, including products based on natural components, used in industries. The main objective of the work was to synthesize a polymeric nanoparticle with the ethanolic extract of Syzyium malaccense leaves, using poly-n-butyl-cyanocrylate (PBCA) and carry out its physicochemical and morphological characterization, carrying out the following analyses: Electronic Microscopy Scanning (SEM), Thermogavimetry (TG), Differential Thermal Analysis (ATD) and Infrared Absorption Spectroscopy (EAIV). In the morphological and physical-chemical analyzes of the nanostructure formed, it is noted that the nanostructure undergoes an endothermic reaction when subjected to high temperature, in addition to having greater mass loss when compared to the extract, with suggestions of the presence of nanoparticles with ethanolic leaf extract of Syzyium malaccense. It is recommended that further confirmatory tests be carried out to confirm the real percentage of nanostructure formation. Furthermore, the photoprotection capacity of Syzyium malaccense leaf extract was determined and, calculated using the Mansur method, a Sun Protection Factor (SPF) of 4.5 was determined, with the need for better compliance with the minimum requirements required. by the National Health Surveillance Agency (ANVISA).