Changes in the removal of blood lactate induced by obesity

• DOI: 10.22533/at.ed.159222217016

• Palavras-chave: Obesity, lactate, metabolism, adipose tissue, liver function.

• Keywords: Obesity, lactate, metabolism, adipose tissue, liver function.

• Abstract:

  In the present study, it was found that lactate in obese individuals has a normal physiology in relation to non-obese individuals, but the time for this substrate to fall becomes slower in individuals who have a greater stock of lipids. This factor can be explained by the tendency to liver problems, as the liver is responsible for metabolizing 30% of the lactate produced in the body, suggesting that the inadequate functioning of this organ causes a slow process in the removal of this substrate from the circulation. As shown in the results of our study, although the obese were not sick, they presented serum parameters slightly above or close to the reference limits, so that they may have something abnormal in their health.
  Alkaline phosphatase concentrations (FAL (p = 0,03), and the enzymes AST (NO = 24 and O = 37,4 U/L), ALT (NO = 40,8 and O = 54,2 U/L) and g-GT (NO = 5,0 and O = 10 U/L) showed a significant increase in obese individuals. Due to the observed increase in concentrations (NO = 125 and O = 198 U/L) in CK in obese individuals we can suggest that they have micro muscular injuries, with an increase in H+ and lactate production. Adipose tissue is involved in other functions besides lactate production, such as the secretion of other substances that have an important metabolic role in the body. This work suggests the importance of adipose tissue as a producer of energy substrate for the organism as well as the importance of the liver in the metabolism of lactate in obese and non-obese individuals.

• Número de páginas: 20