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Bilateral Stellar Cataract due to prolonged use of Chlorpromazine

Opacification of the lens can occur due to several causes and risk factors. With the increase in the chronic use of medications, cataracts related to these drugs are gaining prominence in terms of their worldwide prevalence and knowing what they are is of vital importance in medical practice.
Chlorpromazine, a phenothiazine derivative, is a medication widely used in psychiatry to treat psychosis, especially in cases of schizophrenia.
Since 1964, there have been published articles correlating the use of this medication with the appearance of ocular changes. The leaflet recommends regular ophthalmological and hematological control in various forms. In addition to being clear as a reaction whose frequency is unknown, pigmentary deposits in the anterior segment of the eye.

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Bilateral Stellar Cataract due to prolonged use of Chlorpromazine

  • DOI: https://doi.org/10.22533/at.ed.159492423018

  • Palavras-chave: Antipsychotics; Cataract; Chlorpromazine; Crystalline; Lens diseases

  • Keywords: Antipsychotics; Cataract; Chlorpromazine; Crystalline; Lens diseases

  • Abstract:

    Opacification of the lens can occur due to several causes and risk factors. With the increase in the chronic use of medications, cataracts related to these drugs are gaining prominence in terms of their worldwide prevalence and knowing what they are is of vital importance in medical practice.
    Chlorpromazine, a phenothiazine derivative, is a medication widely used in psychiatry to treat psychosis, especially in cases of schizophrenia.
    Since 1964, there have been published articles correlating the use of this medication with the appearance of ocular changes. The leaflet recommends regular ophthalmological and hematological control in various forms. In addition to being clear as a reaction whose frequency is unknown, pigmentary deposits in the anterior segment of the eye.

  • Rafaela Moreira de Oliveira
  • Luciane Bugmann Moreira
  • Fernando Cotlinski Filho
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