NEUROIMAGING BIOMARKERS FOR ASSESSING THE PROGRESSION OF MYASTHENIA GRAVIS

• DOI: https://doi.org/10.22533/at.ed.1595222516054

• Palavras-chave: Myasthenia Gravis; Biomarkers; Neuroimaging

• Keywords: Myasthenia Gravis; Biomarkers; Neuroimaging

• Abstract:

  This thesis explores the use of neuroimaging biomarkers as essential tools for assessing the progression of Myasthenia Gravis (MG). MG is a chronic autoimmune disease that affects neuromuscular transmission, resulting in muscle weakness and fatigue. Assessing the progression of MG is fundamental for clinical management and for personalizing treatment. The thesis investigates how advanced neuroimaging techniques, such as magnetic resonance imaging (MRI), positron emission tomography (PET) and MR spectroscopy (MRS), can provide objective and quantitative insights into the brain changes associated with MG. It also discusses the challenges and future prospects in the clinical use of these biomarkers.