BETALAINS AS ADJUVANT FOR THE TREATMENT OF OBESITY AND ASSOCIATED DISEASES AND A SIMPLE METHOD TO ISOLATE THEM FROM BEET ROOTS

• DOI: 10.22533/at.ed.1592302215062

• Palavras-chave: Beetroot; betalains; obesity; antioxidants; inflammation; oxidative stress.

• Keywords: Beetroot; betalains; obesity; antioxidants; inflammation; oxidative stress.

• Abstract:

  Obesity is one of the most important public health problems and involves a multifarious process including environmental and genetic factors. Several studies have shown a close relationship between a high body mass index (BMI), low-grade chronic inflammation and oxidative stress in humans. Natural pigments known as betalains have significant antioxidant properties through the direct elimination of free radicals and a notable role in the restoration of the balance of redox processes in the body. This review reflects the effect of betalains in the signaling pathways of obesity and associated diseases as type 2 diabetes mellitus (T2DM) and dyslipidemia. All studies on animal models and humans were critically analyzed. Results discussed here contributed to the fact that different betalain sources have become not only the raw material of food colorants but also therapeutic agents that may play an important role in a multimodal approach to treat the negative effects of obesity and associated comorbidities. A few-steps method to prepare a betalain supplement is also presented in this work.

• Número de páginas: 13