Bel laser®: a photodepilation protocol combining high-performance laser technologies with a topical formulation designed to protect the skin barrier; clinical evaluation of efficacy, safety, tolerability, and skin quality

• DOI: https://doi.org/10.22533/at.ed.51572112601066

• Palavras-chave: Laser photoepilation; skin barrier; niacinamide; skin tolerability; skin quality; clinical safety.

• Keywords: Laser photoepilation; skin barrier; niacinamide; skin tolerability; skin quality; clinical safety.

• Abstract:

  Laser hair removal is widely used for long-term reduction of unwanted hair; however, the thermal stimulus generated during the procedure can cause transient discomfort, a perifollicular inflammatory response, and temporary alterations in the skin barrier. In this context, topical formulations with moisturizing and anti-inflammatory properties can serve as adjunctive strategies to improve tolerability and skin quality. This study aimed to evaluate the perceived clinical efficacy, safety, tolerability, and impact on skin quality of a laser hair removal protocol combined with the application of a topical formulation designed to protect the skin barrier. This is a prospective observational clinical study conducted with 10 patients, aged 21 to 44 years, with Fitzpatrick phototypes II to V, who underwent between 5 and 10 sessions on different body regions. The protocol utilized diode laser platforms combined with the topical application of a formulation containing niacinamide, Aloe vera, humectants, and functional silicones. Outcomes were assessed using a questionnaire based on Patient-Reported Outcomes (PROs), including pain, tolerability, reduction in hair growth, skin quality, satisfaction, and adverse events. The results demonstrated low pain perception (VAS between 0 and 2), high tolerability, progressive reduction in hair growth, thinning of the hair shaft, improvement in skin texture, reduction in folliculitis, and greater uniformity of skin tone. No relevant adverse events were observed. The findings suggest that the combination of laser hair removal and a topical formulation may represent a promising strategy, although controlled studies are needed.