RECENT ADVANCES IN DIAGNOSTIC, THERAPEUTIC AND PROGNOSTIC STRATEGIES FOR TRAUMATIC BRAIN INJURY

• DOI: https://doi.org/10.22533/at.ed.1594672409077

• Palavras-chave: Traumatic brain injuries; Advanced diagnosis; Innovative treatment.

• Keywords: Traumatic brain injuries; Advanced diagnosis; Innovative treatment.

• Abstract:

  Objective: To explore the latest diagnostic, therapeutic and prognostic strategies for the management of patients with Traumatic Brain Injury. Methodology: Using the PubMed - MEDLINE database with specific terms such as "Traumatic brain injury", "TBI", and "Recent advances", a rigorous selection of literature was carried out, resulting in 16 articles pertinent to the topic. Review: Advances in intracranial pressure monitoring and imaging technologies such as Positron Emission Tomography (PET), along with the development of new biomarkers, have significantly improved the early diagnosis of LTCs. This has a positive impact on the prognosis. The implementation of multimodal monitoring, which includes technologies such as Brain Tissue Oxygen Tension Monitoring (PetO2), Pressure Reactivity Index (PRx) and Continuous Electroencephalography (cEEG), has enriched the management of Traumatic Brain Injury (TBI). Final Considerations: Brain microdialysis is crucial for identifying post-trauma biochemical and metabolic changes, allowing for more personalized therapies. Furthermore, pharmacological research is vital to develop more effective treatments for moderate to severe cases of TBI, aiming to improve clinical outcomes and quality of life for patients.