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DIAGNOSTIC ADVANCES IN CUTANEOUS MELANOMA: INTEGRATING TECHNIQUES AND MARKERS FOR ACCURATE DETECTION OF METASTASES

This study presents an integrative review focused on diagnostic methods to detect metastases in cutaneous melanoma, emphasizing advanced imaging techniques, molecular markers and recent technological advances. A systematic search was conducted in the PubMed database, resulting in 79 relevant studies. After inclusion and exclusion criteria, five studies were selected for analysis. The review highlights the importance of histological features in predicting micrometastases in sentinel lymph nodes, emphasizing the significance of risk stratification in patients with stage IIIA melanoma with micrometastases, highlighting the role of advanced imaging techniques such as PET and MRI. Predictors of metastases in non-sentinel lymph nodes in cutaneous melanoma depend on the integration of molecular markers and imaging techniques in risk assessment. 

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DIAGNOSTIC ADVANCES IN CUTANEOUS MELANOMA: INTEGRATING TECHNIQUES AND MARKERS FOR ACCURATE DETECTION OF METASTASES

  • DOI: https://doi.org/10.22533/at.ed.1594502405062

  • Palavras-chave: Cutaneous melanoma; Diagnostic methods; Metastases.

  • Keywords: Cutaneous melanoma; Diagnostic methods; Metastases.

  • Abstract:

    This study presents an integrative review focused on diagnostic methods to detect metastases in cutaneous melanoma, emphasizing advanced imaging techniques, molecular markers and recent technological advances. A systematic search was conducted in the PubMed database, resulting in 79 relevant studies. After inclusion and exclusion criteria, five studies were selected for analysis. The review highlights the importance of histological features in predicting micrometastases in sentinel lymph nodes, emphasizing the significance of risk stratification in patients with stage IIIA melanoma with micrometastases, highlighting the role of advanced imaging techniques such as PET and MRI. Predictors of metastases in non-sentinel lymph nodes in cutaneous melanoma depend on the integration of molecular markers and imaging techniques in risk assessment. 

  • Ana Leticia Rabelo
  • Marina Silva Prado
  • Lara Caldeira
  • Angélica Lupinacci de Araújo Santos
  • Natália Rufino
  • Fernanda Dourado
  • Júlia Tamiozzo Benini
  • Julia Lopes Hemza
  • Isa Glenda Oliveira da Rocha
  • Amanda Tollini de Moraes
  • Laura de Almeida Peralta
  • Marianne Ritter Afonso
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