Associação entre Pênfigo Foliáceo e Tumor Neuroendócrino Pancreático: um relato de caso

• DOI: https://doi.org/10.22533/at.ed.820811125181112

• Palavras-chave: Pênfigo; Tumores Neuroendócrinos; Neoplasias Intestinais

• Keywords: Pemphigus; Neuroendocrine Tumors; Intestinal Neoplasms

• Abstract: The scientific literature on pemphigus and neuroendocrine neoplasms (NENs) informs about the complexity and implications of these clinical conditions. However, research on the topic is still limited. Neuroendocrine neoplasms are a group of epithelial pathologies characterized by neuroendocrine differentiation, which can originate in various organs. Pemphigus is a group of blistering disorders characterized by acantholysis, which is the loss of adhesion between keratinocytes, resulting in the formation of intraepithelial blisters in mucous membranes and the skin. They can be the first clinical manifestation of other pathologies. The early detection of neuroendocrine neoplasms, often asymptomatic in the initial stages, is crucial to optimize the chances of effective treatment. However, the silent evolution of many of these tumors and the difficulty in identifying early signs can result in late diagnoses, limiting therapeutic options such as surgical resection.