PHARMACEUTICAL CARE AND ASSISTANCE IN THE USE OF SOY PROTEIN ISOLATE FOR MENOPAUSAL AND POSTMENOPAUSAL WOMEN: A SYSTEMATIC LITERATURE REVIEW

• DOI: https://doi.org/10.22533/at.ed.1594952423108

• Palavras-chave: Glycine max; Fogachos; Alternative therapy.

• Keywords: Glycine max; Fogachos; Alternative therapy.

• Abstract:

  Currently, the use and consumption of soybeans is one of the topics that is arousing interest among researchers, health agencies and departments and populations around the world. Belonging to the legume family, soya is the only source of protein of plant origin that has all the essential amino acids and is considered to be of high biological value. Its beans are rich in fats, with a predominance of polyunsaturated fatty acids such as linolenic acid (omega 3) and linoleic acid (omega 6). Soya also contains around 1 to 3 milligrams (mg) of isoflavones per gram (g) of protein, which has aroused interest among researchers because it is rich in this phytoestrogen, considered to be a non-hormonal chemical compound with a structure similar to that of human estrogen hormones, which, in addition to antioxidant properties, play a role as selective modulators of estrogen receptor SERMs. In recent decades, interest in the management of menopausal patients has increased, largely due to improved life expectancy, which means that the female population is expected to live around a third of their lives after the menopause. The aim of this study is to carry out a systematic review of the literature on the effects of selective estrogen receptor modulators (SERMs) in pre- and post-menopausal women. The methodology used is a strategic research study with descriptive objectives, a qualitative approach using a systematic literature review procedure and an exploratory research technique to acquire new knowledge about selective modulators in menopausal and post-menopausal women, including a simultaneous analysis of the articles used as inclusion criteria, which were discussed in order to update the scientific and general community on the subject of the research using the descriptors. Considering the studies carried out and some controversial results regarding the effects of soy isoflavones as an alternative treatment for menopausal symptoms, further research is essential in order to confirm the effectiveness of this therapy, as well as to disseminate knowledge about the benefits of soy for the population. Therefore, the aim of this research is to evaluate the effectiveness of soy protein supplementation on menopausal and post-menopausal symptoms and the appearance of side effects.