IMMUNOLOGICAL ASPECTS OF GRAFT-VERUS-HOST DISEASE IN PATIENTS WITH ACUTE MYELOID LEUKEMIA

• DOI: 10.22533/at.ed.15931002306122

• Palavras-chave: Graft Versus Host Disease. Acute Myeloid Leukemia. Immune system. T Cells. Hematological Neoplasms. Bone marrow transplant.

• Keywords: Graft Versus Host Disease. Acute Myeloid Leukemia. Immune system. T Cells. Hematological Neoplasms. Bone marrow transplant.

• Abstract:

  Graft Versus Host Disease has as its main focus the patient's immune system, as well as the marrow received, and may arise from complications after transplantation, very common in patients with Leukemia. The present study had the function of carrying out the analysis of the cellular pathway to combat the pathology in question and how the disease acts in the transplanted person's body so that an immunological understanding of the reaction is possible and thus the possibility of alternative options for treatment. most effective treatment of the disease. Data analysis was carried out using phenomenological methods, which seeks to clarify in a broader way through other research already carried out previously, to reach current considerations on a given topic. After analyzing all the research instruments collected, it was possible to see a higher incidence of Acute Myeloid Leukemia in male patients, and most cases of Graft Versus Host Disease in elderly people of the same sex, due to deficiency in the production of T cells. With everything that has been pointed out, this research aims to clarify the contribution to the development of future treatments for Graft Versus Host Disease.