ARRHYTHMOGENIC CARDIOMYOPATHY OF THE RIGHT VENTRICLE: CLINICAL AND PHYSIOPATHOLOGICAL ASPECTS

• DOI: https://doi.org/10.22533/at.ed.1594542414067

• Palavras-chave: Displasia arritmogênica do ventrículo direito, fisiopatologia, clínica e diagnóstico.

• Keywords: Arrhythmogenic dysplasia of the right ventricle, pathophysiology, clinic and diagnosis.

• Abstract: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a progressive hereditary clinical entity, physiologically characterized by mutations encoding the heart muscle, and predominantly affects the right ventricle. The objective of the study carried out is to evaluate and consolidate the main available evidence on arrhythmogenic right ventricular cardiomyopathy and its main clinical and pathophysiological aspects, using studies and articles published in the last 5 years.  Integrative, exploratory and qualitative review of research, through searches in the scientific databases PubMed, VHL and SciELO. The established inclusion criteria were: original articles available in electronic format, in full, written in Portuguese, English or Spanish, with a time limit from 2019 to 2024. The investigation was carried out in March 2024. With the research carried out, 360 articles were found, 210 of these were selected for reading and, according to the objective of this work, 10 were included in the research. In summary, despite being rare, ARVC is related to potentially fatal changes, such as malignant arrhythmias that lead to sudden death, which makes evident the importance of conservative and in-depth studies to define the incidence in the general population, which is still ill. known and its etiopathogenic mechanism, such as genetic or acquired disease, or sequelae of myocarditis.