Analyze of Sunflower Oil incorporation in Poly(acrylic acid)/ Chitosan Sponges Using Thin Plate Spline Interpolation Method
Analyze of Sunflower Oil incorporation in Poly(acrylic acid)/ Chitosan Sponges Using Thin Plate Spline Interpolation Method
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DOI: 10.22533/at.ed.3173282323082
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Palavras-chave: curativo; modelagem; biomaterial; esponja
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Keywords: wound dressing; modelling; biomaterial; sponge
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Abstract: Chitosan/PAA sponges (potential applied in wound healing) were produce and loaded with serum and Dersani®. Thin Plate Spline interpolation method (TPSIM) was used to evaluate the effect of composition and the time in the sponges capability of fluid incorporation. A surface composed of experimental and interpolated data were obtained. polynomial regression with multiple independent variables was used to evaluate the contribution of each variable. Scanning electron microscopy (MEV), x-Ray diffraction (XRD) and Differential Scanning Calorimetry (DSC) were done. The composition affects the sponge's morphology. Materials amorphization occurred due chitosan/PAA interaction as stated by DSC and XRD. TPSIM showed that the composition has a significantly greater individual contribution in fluid absorption. The time individually contribution is small. However, the interaction between time and composition are responsible for the non-linear shape of the curve and have relevant impact in fluid incorporation.
- Talita Goulart da Silva
- Tiago dos Santos Mendonça
- Raquel de Souza Ribeiro
- Cristiane Evelise Ribeiro da Silva
- Sonia Letichevsky
- Roberta Helena
- Roberta Helena Mendonça