ANALYSIS OF THE USE OF NANOPARTICLES CONTAINING DAPSONE IN THE TREATMENT OF SKIN WOUNDS: A LITERATURE REVIEW

• DOI: https://doi.org/10.22533/at.ed.1594812429082

• Palavras-chave: SKIN WOUNDS, NANOPARTICLES, DAPSONE.

• Keywords: SKIN WOUNDS, NANOPARTICLES, DAPSONE.

• Abstract:

  This literature review aimed to evaluate the efficiency of dapsone encapsulated by nanoparticles in the treatment of skin wounds. To achieve this objective, as a way to perform a primary selection of articles, strings were applied to the Scielo and PubMed platforms. Data were collected for the years 2012 to 2020. The articles found were subjected to a secondary selection, through the application of previously defined inclusion and exclusion criteria and submitted to a quality assessment scale. As a result, one article was found on the Scielo platform and fourteen on the PubMed platform. After applying the secondary selection, 6 articles were selected for full analysis, 4 for abstract analysis and 6 were excluded. Of the articles selected for analysis, many had similarities in the method of characterization of nanoparticles and in the results when suggesting the use of nanosystems as an alternative to the treatment of skin wounds. Regarding the differences, the most important ones are the method of drug administration (topical, oral or unspecified) and the skin wound targeted by the research (leprosy, acne or unspecified). It was concluded that the use of dapsone in nanosystems is promising for the treatment of skin wounds.