ANALYSIS OF THE EPIDEMIOLOGICAL PROFILE AND EFFECTIVENESS OF THE USE OF DUAL THERAPY IN HIV PATIENTS AT THE INFECTOLOGY OUTPATIENT OF HOSPITAL SANTA CASA DE MISERICÓRDIA DE VITÓRIA/ES

• DOI: https://doi.org/10.22533/at.ed.1594392418043

• Palavras-chave: HIV. Dolutegravir. Darunavir.

• Keywords: HIV. Dolutegravir. Darunavir.

• Abstract:

  Objective: The objective of the work is to evaluate the effectiveness of using dual therapy in HIV treatment and the epidemiological profile of patients at the Infectious Diseases Outpatient Clinic of Hospital ``Santa Casa de Misericórdia de Vitória``. Method: This is an observational, analytical and descriptive study. The initial sample was selected from a list of patients undergoing HIV treatment at the infectious disease outpatient clinic and selection of patients on dual therapy. Information on the epidemiological profile was collected and efficacy was defined by the suppression of the viral load within a period of 6 months to 1 year after the start of dual therapy. Results: A total of 120 patients met the study inclusion criteria and 95 remained after the exclusion criteria. 63 patients were using dual therapy with DTG + DRV/r, 26 were using DTG + 3TC and 6 patients were using DRV + 3TC. The main reason for changing therapy was due to toxicity from the triple regimen. The average age of the sample was 60.6 years. Efficacy of dual therapy was achieved in 87 patients (91.6%). Conclusion: It is possible to verify the high effectiveness of dual therapy in suppressing viral load, which makes it an appropriate alternative for cases with contraindications or intolerant to the triple regimen.