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The Relationship between the Vagus Nerve, Autism and Genomic Neuroscience: Unlocking Therapeutic Potential

Autism Spectrum Disorder (ASD) is often accompanied by difficulties in social behavior and emotion regulation, potentially associated with dysfunctions of the autonomic nervous system. Vagus nerve stimulation (VNS), a neuromodulation technique used in epilepsy and depression, has shown promise in improving behavior in individuals with ASD. This review examines the existing literature on the effects of VNS on behavior in ASD, finding preliminary evidence of its potential benefits, regardless of its effects on seizure frequency and mood. However, more rigorous studies are needed to confirm these findings.

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The Relationship between the Vagus Nerve, Autism and Genomic Neuroscience: Unlocking Therapeutic Potential

  • DOI: https://doi.org/10.22533/at.ed.1594982408112

  • Palavras-chave: Autism Spectrum Disorder, Vagus Nerve Stimulation, Autonomic Nervous System, Social Behavior, Emotion Regulation

  • Keywords: Autism Spectrum Disorder, Vagus Nerve Stimulation, Autonomic Nervous System, Social Behavior, Emotion Regulation

  • Abstract:

    Autism Spectrum Disorder (ASD) is often accompanied by difficulties in social behavior and emotion regulation, potentially associated with dysfunctions of the autonomic nervous system. Vagus nerve stimulation (VNS), a neuromodulation technique used in epilepsy and depression, has shown promise in improving behavior in individuals with ASD. This review examines the existing literature on the effects of VNS on behavior in ASD, finding preliminary evidence of its potential benefits, regardless of its effects on seizure frequency and mood. However, more rigorous studies are needed to confirm these findings.

  • Fabiano de Abreu Agrela Rodrigues
  • Luiz Felipe Chaves Carvalho
  • Elodia Avila
  • Clara Amorim Ferreira Amaral
  • Velibor Kostić
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