THE INFLUENCE OF THE INTESTINAL MICROBIOTA ON CARDIOVASCULAR HEALTH: AN INTEGRATIVE REVIEW

• DOI: 10.22533/at.ed.15934323060610

• Palavras-chave: Gut microbiota. Cardiovascular diseases. Cardiovascular Health.

• Keywords: Gut microbiota. Cardiovascular diseases. Cardiovascular Health.

• Abstract:

  Introduction: The gut microbiota plays a key role in human health, influencing various physiological processes in cardiovascular health. Objective: To analyze the scientific research that investigates the relationship between the intestinal microbiota and cardiovascular health, in particular the existing evidence on how the composition of the intestinal microbiota affects the development of cardiovascular diseases. Methodology: Articles relevant to the work were selected, including clinical trial, meta-analysis, literature review and systematic literature review, through the platform's data base PubMed, using the keywords "Gut microbiota" and "Heart disease". Results: The studies investigated different aspects of the relationship between intestinal microbiota and cardiovascular health, including the influence of intestinal dysbiosis, microbial diversity, metabolites produced by the microbiota and the immunological mechanisms involved. The results suggest that alterations in the composition of the intestinal microbiota may be associated with an increased risk of cardiovascular diseases, including atherosclerosis, hypertension and ischemic heart disease. Conclusion: Based on the integrative literature review, there is growing evidence that the gut microbiota plays a relevant role in cardiovascular health. Understanding the mechanisms involved in this relationship can provide important insights for the development of new therapeutic strategies and interventions based on the modulation of the intestinal microbiota. However, further studies are needed to fully elucidate the underlying mechanisms and establish effective interventions to improve cardiovascular health through manipulation of the gut microbiota.