RENAL SYMPATHETIC DENERVATION IN THE MANAGEMENT OF RESISTANT HYPERTENSION: A REVIEW OF CURRENT EVIDENCE

• DOI: 10.22533/at.ed.1593502307075

• Palavras-chave: Resistant Arterial Hypertension; Renal Sympathetic Denervation; Treatment.

• Keywords: Resistant Arterial Hypertension; Renal Sympathetic Denervation; Treatment.

• Abstract:

  Goal: To evaluate the efficacy and safety of Renal Sympathetic Denervation (RSD) as a therapeutic approach in the management of resistant hypertension, through the analysis of recent clinical and experimental studies. Additionally, it aims to examine current evidence supporting its clinical use, discuss indications and contraindications, and identify areas where further research is needed to improve understanding and clinical practice. Methodology: A bibliographic review was carried out through searches in the PubMed Central (PMC) and SciELO (Scientific Electronic Library Online) databases. 196 articles were found and, after applying the inclusion criteria, 24 studies were selected to compose the collection. Results: Several types of studies reviewed indicate that Renal Sympathetic Denervation (RSD) is effective and safe in the management of resistant hypertension, both as a stand-alone treatment and as adjunctive therapy. The effects of this treatment demonstrated a reduction in blood pressure for at least 6 months after the procedure, with no complications and no kidney damage for at least 7 years after the intervention. Final considerations: Although more research is needed to confirm the long-term results, it is possible to associate Renal Sympathetic Denervation not only as an effective and safe procedure, but also as a relevant intervention for the improvement of cardiovascular morbidity and mortality.